Glutamate Excitotoxicity Kills Brain Cells

We’re working on drugs that will help eliminate Excitotoxicity

Excess free glutamate in the brain causes “Excitotoxicity” which kills brain cells. 

Excitotoxicity is a serious underlying condition in Brain Cancer, Epilepsy, Alzheimer’s Disease, Amyotrophic Lateral Sclerosis (ALS), Closed Head Injury and Stroke.


MetVital has developed a patented small molecule “AEO” that binds up glutamate in the bloodstream.

This causes a molecular imbalance, forcing the brain to excrete glutamate across the blood-brain barrier, and lower free brain glutamate.  The lower glutamate levels protect the brain from excitotoxicity without causing side-effects in animal models.

MetVital is conducting clinical trials to develop AEO as a potential drug for a variety of brain conditions.